BIF401 GDB Solution Spring 2021

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BIF401 GDB SOLUTION SPRING 2021

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TOPIC:

How Bioinformatics Helped to Discover the Drug for Covid-19


SOLUTION:

 

Bioinformatics used the following sequential steps to discover the vaccine or drug for Covid-19 

1) Bioinformatics database 

2) Sequence comparison 

3) Phylogenetic analysis 

4) Structure modelling 

5) Drug design 


The virus. From the sequence analysis to the final prediction of the drug candidate, several steps are required, which can be divided into five sections: retrieving the virus sequence from the nucleic acid database, analyzing sequence data by comparing it with other virus sequences, phylogeny analysis of virus sequences to find out how the target virus, the evolved from others, computer modeling of key viral proteins as drug targets, and finally testing various drug molecules against viral proteins to detect inhibitory activities.




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